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2009•Journal of Pathogen BiologyRequires access

Clinical study of and Norovirus antigen detection in feces from patients with acute diarrhea.

Shaogang Li, Xiaoli Li, Chenghong Yin

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Abstract

Objective To explore the clinical characteristics of Norovirus diarrhea and determine the levels of fecal Norovirus antigens for clinical diagnosis. Methods Fecal specimens were collected from 297 patients with acute diarrhea seen at Beijing Friendship Hospital from 2007-10-2008-02. Norovirus antigens in the stool were detected by an enzyme-linked immunosorbent assay (ELISA),and then data were analyzed. Results Of the 297 patients,100 (33.7%) were positive for Norovirus detected by ELISA. Conclusion Norovirus is a major cause of diarrhea,and testing for fecal Norovirus antigens is helpful in diagnosis of the disease.

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Objective To explore the clinical characteristics of Norovirus diarrhea and determine the levels of fecal Norovirus antigens for clinical diagnosis. Methods Fecal specimens were collected from 297 patients with acute diarrhea seen at Beijing Friendship Hospital from 2007-10-2008-02. Norovirus antigens in the stool were detected by an enzyme-linked immunosorbent assay (ELISA),and then data were analyzed. Results Of the 297 patients,100 (33.7%) were positive for Norovirus detected by ELISA. Conclusion Norovirus is a major cause of diarrhea,and testing for fecal Norovirus antigens is helpful in diagnosis of the disease.

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Available abstract

Objective To explore the clinical characteristics of Norovirus diarrhea and determine the levels of fecal Norovirus antigens for clinical diagnosis. Methods Fecal specimens were collected from 297 patients with acute diarrhea seen at Beijing Friendship Hospital from 2007-10-2008-02. Norovirus antigens in the stool were detected by an enzyme-linked immunosorbent assay (ELISA),and then data were analyzed. Results Of the 297 patients,100 (33.7%) were positive for Norovirus detected by ELISA. Conclusion Norovirus is a major cause of diarrhea,and testing for fecal Norovirus antigens is helpful in diagnosis of the disease.

Key concepts: Norovirus, Diarrhea, Feces, Antigen, Acute diarrhea, Medicine, Virology, Immunology

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