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2007•PubMedOpen access

Disseminated intravascular coagulation and a negative D-dimer test.

Alina Constantinescu, Paul B. Berendes, M-D Levin

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Abstract

The diagnosis of disseminated intravascular coagulation (DIC) requires the presence of a fibrin-related marker. D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic DIC with a false-negative D-dimer test. Repeating the test using a different D-dimer assay as well as the measurement of other fibrinolysis markers confirmed the diagnosis of DIC.

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The diagnosis of disseminated intravascular coagulation (DIC) requires the presence of a fibrin-related marker. D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic DIC with a false-negative D-dimer test. Repeating the test using a different D-dimer assay as well as the measurement of other fibrinolysis markers confirmed the diagnosis of DIC.

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OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The diagnosis of disseminated intravascular coagulation (DIC) requires the presence of a fibrin-related marker. D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic DIC with a false-negative D-dimer test. Repeating the test using a different D-dimer assay as well as the measurement of other fibrinolysis markers confirmed the diagnosis of DIC.

Key concepts: D-dimer, Disseminated intravascular coagulation, Medicine, Fibrinolysis, Fibrin, Coagulation, Pathology, Internal medicine

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