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[Clinical analysis of vocal cord leukoplakia in 32 cases].

Hai Zhang, X M Chen, Z H Li

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Abstract

OBJECTIVE: To investigate the types and curative effects of the leukoplakia of the vocal cord. METHOD: From 1990 to 1996, 32 patients (38 sides) with leukoplakia of vocal cord were operated in our hospital, postoperative follow-up ranged from 2 to 7 years. RESULT: There were eighteen cases of simple leukoplakia and fourteen cases of leukoplakia with mild, moderate and severe atypical hyperplasia in this study. None of simple leukoplakia had malignant change. But there were 33%, 75% and 75% of cases had malignant change in the leukoplakia with mild, moderate and severe atypical hyperplasia respectively. To surgical methods, there was no significant difference, in the rate of malignant change either by the microlaryngoscopy or thyrotomy. CONCLUSION: Simple leukoplakia can be cured. More attention should be paid to the leukoplakia with any types of atypical hyperplasia during clinical management. The postoperative results were not depend on the surgical methods.

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What this paper is about

OBJECTIVE: To investigate the types and curative effects of the leukoplakia of the vocal cord. METHOD: From 1990 to 1996, 32 patients (38 sides) with leukoplakia of vocal cord were operated in our hospital, postoperative follow-up ranged from 2 to 7 years. RESULT: There were eighteen cases of simple leukoplakia and fourteen cases of leukoplakia with mild, moderate and severe atypical hyperplasia in this study. None of simple leukoplakia had malignant change. But there were 33%, 75% and 75% of cases had malignant change in the leukoplakia with mild, moderate and severe atypical hyperplasia respectively. To surgical methods, there was no significant difference, in the rate of malignant change either by the microlaryngoscopy or thyrotomy. CONCLUSION: Simple leukoplakia can be cured. More attention should be paid to the leukoplakia with any types of atypical hyperplasia during clinical management. The postoperative results were not depend on the surgical methods.

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Available abstract

OBJECTIVE: To investigate the types and curative effects of the leukoplakia of the vocal cord. METHOD: From 1990 to 1996, 32 patients (38 sides) with leukoplakia of vocal cord were operated in our hospital, postoperative follow-up ranged from 2 to 7 years. RESULT: There were eighteen cases of simple leukoplakia and fourteen cases of leukoplakia with mild, moderate and severe atypical hyperplasia in this study. None of simple leukoplakia had malignant change. But there were 33%, 75% and 75% of cases had malignant change in the leukoplakia with mild, moderate and severe atypical hyperplasia respectively. To surgical methods, there was no significant difference, in the rate of malignant change either by the microlaryngoscopy or thyrotomy. CONCLUSION: Simple leukoplakia can be cured. More attention should be paid to the leukoplakia with any types of atypical hyperplasia during clinical management. The postoperative results were not depend on the surgical methods.

Key concepts: Medicine, Leukoplakia, Oral leukoplakia, Cord, Atypical hyperplasia, Hyperplasia, Surgery, Pathology

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