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1996•Journal of the Korean Chemical SocietyRequires access

Synthetic Studies on the Nucleophilic Adducts of Thiophenol Derivatives to 4'-[N-(9-Acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide

Tae Rin Kim, Dong In Chung, Sang Yong Pyun

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Abstract

A simple and efficient new synthetic method of 4'-[N-(9-acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide(AMQD, 5) was developed and six new nucleophilic adducts(6a-6f) were prepared by the addition of thiophenol derivatives to AMQD. The structures of these compounds were confirmed by elemental analysis, mass, ir and nmr spectra.

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What this paper is about

A simple and efficient new synthetic method of 4'-[N-(9-acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide(AMQD, 5) was developed and six new nucleophilic adducts(6a-6f) were prepared by the addition of thiophenol derivatives to AMQD. The structures of these compounds were confirmed by elemental analysis, mass, ir and nmr spectra.

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Available abstract

A simple and efficient new synthetic method of 4'-[N-(9-acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide(AMQD, 5) was developed and six new nucleophilic adducts(6a-6f) were prepared by the addition of thiophenol derivatives to AMQD. The structures of these compounds were confirmed by elemental analysis, mass, ir and nmr spectra.

Key concepts: Thiophenol, Nucleophile, Adduct, Chemistry, Nucleophilic addition, Medicinal chemistry, Combinatorial chemistry, Organic chemistry

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Synthetic Studies on the Nucleophilic Adducts of Thiophenol Derivatives to 4'-[N-(9-Acridinyl)]-1'-(N-methanesulfonyl)-3'-methoxyquinonediimide — Research Paper | ScholarLens