Necrotic seminoma of the testis: establishing the diagnosis with Masson trichrome stain and immunostains.
Barbara D. Florentine, Arno A. Roscher, Jerry Garrett, Nancy E. Warner
Abstract
Barbara D. Florentine, Arno A. Roscher, Jerry Garrett, Nancy E. Warner
Abstract
○ We describe an infarcted mass in the testis containing ghost cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.
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○ We describe an infarcted mass in the testis containing ghost cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.
Key concepts: Masson's trichrome stain, Seminoma, Pathology, Immunostaining, Trichrome, Trichrome stain, Stain, Staining