2002•Archives of Pathology & Laboratory MedicineRequires access

Necrotic seminoma of the testis: establishing the diagnosis with Masson trichrome stain and immunostains.

Barbara D. Florentine, Arno A. Roscher, Jerry Garrett, Nancy E. Warner

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Abstract

○ We describe an infarcted mass in the testis containing ghost cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.

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What this paper is about

○ We describe an infarcted mass in the testis containing ghost cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.

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Available abstract

○ We describe an infarcted mass in the testis containing ghost cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.

Key concepts: Masson's trichrome stain, Seminoma, Pathology, Immunostaining, Trichrome, Trichrome stain, Stain, Staining

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Necrotic seminoma of the testis: establishing the diagnosis with Masson trichrome stain and immunostains. — Research Paper | ScholarLens