Ion channels and disease : channelopathies
Frances M. Ashcroft
Abstract
Frances M. Ashcroft
Abstract
Preface. Introduction. From Gene to Protein. How Channels Work. Methods for Studying Ion Channels. Voltage-Gated Na+ Channels. Voltage-Gated K+ Channels. Ca-Activated K+ Channels. Inward Rectifier K+ Channels. Voltage-Gated Ca2+ Channels. Voltage-Gated Cl- Channels. Cyclic Nucleotide-Gated Channels. CFTR. Epithelia Na+ Channels. Ligand-Gated Ca2+ Channels. ACh Receptor Channels. Glutamate Receptor Channels. Glycine Receptors. GABA Receptors. Water Channels. Gap Junction Channels. Antibodies to Ion Channels. Ion Channels in Viruses. Ion Channels as Lethal Agents. A Miscellany of Ion Channels. The Last Word. References. Subject Index.
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Preface. Introduction. From Gene to Protein. How Channels Work. Methods for Studying Ion Channels. Voltage-Gated Na+ Channels. Voltage-Gated K+ Channels. Ca-Activated K+ Channels. Inward Rectifier K+ Channels. Voltage-Gated Ca2+ Channels. Voltage-Gated Cl- Channels. Cyclic Nucleotide-Gated Channels. CFTR. Epithelia Na+ Channels. Ligand-Gated Ca2+ Channels. ACh Receptor Channels. Glutamate Receptor Channels. Glycine Receptors. GABA Receptors. Water Channels. Gap Junction Channels. Antibodies to Ion Channels. Ion Channels in Viruses. Ion Channels as Lethal Agents. A Miscellany of Ion Channels. The Last Word. References. Subject Index.
Key concepts: Light-gated ion channel, Ion channel, Ligand-gated ion channel, Inward-rectifier potassium ion channel, Voltage-gated ion channel, Stretch-activated ion channel, Chemistry, Glycine receptor