2012•PubMedOpen access

[The use of ondansetron in acute gastroenteritis. Its impact in a pediatric emergency department].

A Venuta, Eleonora Spaggiari, Paolo Bertolani, F. Balli

Abstract

BACKGROUND: Ondansentron is in consideration in literature for its use in vomiting secondary to acute gastroenteritis in children. OBJECTIVE: To evaluate its usefulness in children with acute gastroenteritis referred to a paediatric emergency department. METHODS: A retrospective study considered 967 children treated with ondansetron (0,06 mg/kg IM) plus oral rehydration, with a control group of 286 children who received only oral rehydration. RESULTS: The time spent into the short-stay observation unit and the total emergency department stay were significantly reduced in children receiving ondansentron. No adverse reactions to the drug were recorded.

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Available abstract

Key concepts: Ondansetron, Medicine, Emergency department, Acute gastroenteritis, Vomiting, Emergency medicine, Retrospective cohort study, Pediatrics