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Composite Sophorae Injection in prevention of toxicity and adverse effects caused by chemotherapeutic agents.

Zhu ZhaoCheng, Huaizhang Wang, Feng Yang

Abstract

Objective To evaluate Composite Sophorae Injection in prevention of toxicity and adverse effects caused by chemotherapeutic agents.Methods Seventy eight cancer patients who underwent chemotherapy and symptomatic treatment were randomly divided into treatment group and control one.In treatment group patients also received Composite Sophorae Injection 20 mL a day for 20 days.Results The incidence rate of toxicity and adverse reactions caused by chemotherapy in the treated group was significantly lower than that in the control group,and Karnofsky score was significantly higher than that in control group.Conclusion Composite Sophorae Injection can reduce the toxicity and adverse effects caused by chemotherapy medicine,and improve quality of life.

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Key concepts: Medicine, Toxicity, Adverse effect, Chemotherapy, Incidence (geometry), Surgery, Internal medicine, Optics