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Concanavalin A : [proceedings]

Tushar K. Chowdhury, Adolph Kurt Weiss

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Abstract

1 Concanavalin A: An Introduction.- I. Background Information.- II. Physical and Chemical Properties of Concanavalin A.- III. Biological Properties of Concanavalin A.- References.- 2 Structure and Function of Concanavalin A.- Abstract.- I. Introduction.- II. Structure of Concanavalin A.- III. Saccharide Binding Function of Concanavalin A.- IV. Multivalent Nature of Con A.- V. A Model for Interactions between Cell Surface Receptors and Cytoplasmic Structures.- References.- 3 Studies on the Combining Sites of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 4 13C NMR Studies of the Interaction of Concanavalin A with Saccharides.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 5 Self-Association, Conformation and Binding Equilibria of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- III. Conclusion.- References.- 6 Studies on the Interaction of Concanavalin A with Glycoproteins.- Abstract.- I. Introduction.- II. Methods.- III. Results.- References.- 7 Interaction of Concanavalin A with the Surface of Virus - Infected Cells.- Abstract.- I. Introduction.- II. Methods, Results, and Discussions.- References.- 8 Concanavalin A as A Quantitative and Ultrastructural Probe for Normal and Neoplastic Cell Surfaces.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 9 Microtubular Proteins and Concanavalin A Receptors.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 10 Effects of Concanavalin a on Cellular Dynamics and Membrane Transport.- Abstract.- I. Introduction.- II. Methods of Procedure.- III. Results.- IV. Discussion.- References.- 11 The Characteristics of Succinylated Con a Induced Growth Inhibition of 3T3 Cells in Tissue Culture.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 12 Cell Cycle Dependent Agglutinability, Distribution of Concanavalin a Binding Sites and Surface Morphology of Normal and Transformed Fibroblasts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 13 Concanavalin A and Other Lectins in the Study of Tumor Cell Surface Organization.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 14 Modification of the Biological Activities of Concanavalin A by Anti-Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 15 Concanavalin A as A Probe for Studying the Mechanism of Metabolic Stimulation of Leukocytes.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 16 Enhanced Cytotoxicity in Mice of Combinations of Concanavalin A and Selected Antitumor Drugs.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 17 Effect of Concanavalin A and Phytohemagglutinin on the Modification of Immunogenicity of Canine Kidney Allografts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- Abstracts.- Evidence for Conformational Changes in Concanavalin A upon Binding of Saccharides as Determined from Solvent Water Proton Magnetic Relaxation Rate Dispersion Measurements.- Magnetic Resonance Studies of Concanavalin A: Location of The Binding Site of Methyl-D-Mannopyranoside.- The Metal Ion Requirements of Concanavalin A.- The Kinetics of Cellular Commitment during Stimulation of Lymphocytes by Concanavalin A.- Isolation of A Glycoprotein Receptor for Concanavalin A from the Outer Surface of Mouse L Cells.- Electron Microscopic Study on Interaction of Concanavalin A with Mouse Lymphosarcoma Cells in Tissue Culture and in Ascites form.- The Effect of Glutaraldehyde Fixation on the Agglutination of Human Erythrocytes by Concanavalin A and Soybean Agglutinin.- Altered Net Cation Transfer Across the Ehrlich Mouse Ascites Tumor Cell During Exposure to Concanavalin A.- Effects of Con A on Frog Nerve and Muscle.- Modification of the Surface Characteristics of Developing Hemopoietic Cells from Normal Human Bone Marrow Revealed Ultrastructurally by the Concanavalin A-Peroxidasediaminobenzidine Technique.- Effects of Succinyl-Con A on the Growth of Normal and Transformed Mouse Fibroblasts.- Endotoxin-Like Activities in Concanavalin A Preparations.- Concanavalin A Induced Inflammation.- Enhanced Immunogenicity of Con A Coated El-4 Leukemia Cells.- List of Contributors.

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1 Concanavalin A: An Introduction.- I. Background Information.- II. Physical and Chemical Properties of Concanavalin A.- III. Biological Properties of Concanavalin A.- References.- 2 Structure and Function of Concanavalin A.- Abstract.- I. Introduction.- II. Structure of Concanavalin A.- III. Saccharide Binding Function of Concanavalin A.- IV. Multivalent Nature of Con A.- V. A Model for Interactions between Cell Surface Receptors and Cytoplasmic Structures.- References.- 3 Studies on the Combining Sites of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 4 13C NMR Studies of the Interaction of Concanavalin A with Saccharides.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 5 Self-Association, Conformation and Binding Equilibria of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- III. Conclusion.- References.- 6 Studies on the Interaction of Concanavalin A with Glycoproteins.- Abstract.- I. Introduction.- II. Methods.- III. Results.- References.- 7 Interaction of Concanavalin A with the Surface of Virus - Infected Cells.- Abstract.- I. Introduction.- II. Methods, Results, and Discussions.- References.- 8 Concanavalin A as A Quantitative and Ultrastructural Probe for Normal and Neoplastic Cell Surfaces.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 9 Microtubular Proteins and Concanavalin A Receptors.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 10 Effects of Concanavalin a on Cellular Dynamics and Membrane Transport.- Abstract.- I. Introduction.- II. Methods of Procedure.- III. Results.- IV. Discussion.- References.- 11 The Characteristics of Succinylated Con a Induced Growth Inhibition of 3T3 Cells in Tissue Culture.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 12 Cell Cycle Dependent Agglutinability, Distribution of Concanavalin a Binding Sites and Surface Morphology of Normal and Transformed Fibroblasts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 13 Concanavalin A and Other Lectins in the Study of Tumor Cell Surface Organization.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 14 Modification of the Biological Activities of Concanavalin A by Anti-Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 15 Concanavalin A as A Probe for Studying the Mechanism of Metabolic Stimulation of Leukocytes.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 16 Enhanced Cytotoxicity in Mice of Combinations of Concanavalin A and Selected Antitumor Drugs.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 17 Effect of Concanavalin A and Phytohemagglutinin on the Modification of Immunogenicity of Canine Kidney Allografts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- Abstracts.- Evidence for Conformational Changes in Concanavalin A upon Binding of Saccharides as Determined from Solvent Water Proton Magnetic Relaxation Rate Dispersion Measurements.- Magnetic Resonance Studies of Concanavalin A: Location of The Binding Site of Methyl-D-Mannopyranoside.- The Metal Ion Requirements of Concanavalin A.- The Kinetics of Cellular Commitment during Stimulation of Lymphocytes by Concanavalin A.- Isolation of A Glycoprotein Receptor for Concanavalin A from the Outer Surface of Mouse L Cells.- Electron Microscopic Study on Interaction of Concanavalin A with Mouse Lymphosarcoma Cells in Tissue Culture and in Ascites form.- The Effect of Glutaraldehyde Fixation on the Agglutination of Human Erythrocytes by Concanavalin A and Soybean Agglutinin.- Altered Net Cation Transfer Across the Ehrlich Mouse Ascites Tumor Cell During Exposure to Concanavalin A.- Effects of Con A on Frog Nerve and Muscle.- Modification of the Surface Characteristics of Developing Hemopoietic Cells from Normal Human Bone Marrow Revealed Ultrastructurally by the Concanavalin A-Peroxidasediaminobenzidine Technique.- Effects of Succinyl-Con A on the Growth of Normal and Transformed Mouse Fibroblasts.- Endotoxin-Like Activities in Concanavalin A Preparations.- Concanavalin A Induced Inflammation.- Enhanced Immunogenicity of Con A Coated El-4 Leukemia Cells.- List of Contributors.

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Available abstract

1 Concanavalin A: An Introduction.- I. Background Information.- II. Physical and Chemical Properties of Concanavalin A.- III. Biological Properties of Concanavalin A.- References.- 2 Structure and Function of Concanavalin A.- Abstract.- I. Introduction.- II. Structure of Concanavalin A.- III. Saccharide Binding Function of Concanavalin A.- IV. Multivalent Nature of Con A.- V. A Model for Interactions between Cell Surface Receptors and Cytoplasmic Structures.- References.- 3 Studies on the Combining Sites of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 4 13C NMR Studies of the Interaction of Concanavalin A with Saccharides.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 5 Self-Association, Conformation and Binding Equilibria of Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- III. Conclusion.- References.- 6 Studies on the Interaction of Concanavalin A with Glycoproteins.- Abstract.- I. Introduction.- II. Methods.- III. Results.- References.- 7 Interaction of Concanavalin A with the Surface of Virus - Infected Cells.- Abstract.- I. Introduction.- II. Methods, Results, and Discussions.- References.- 8 Concanavalin A as A Quantitative and Ultrastructural Probe for Normal and Neoplastic Cell Surfaces.- Abstract.- I. Introduction.- II. Methods.- III. Results and Discussion.- References.- 9 Microtubular Proteins and Concanavalin A Receptors.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 10 Effects of Concanavalin a on Cellular Dynamics and Membrane Transport.- Abstract.- I. Introduction.- II. Methods of Procedure.- III. Results.- IV. Discussion.- References.- 11 The Characteristics of Succinylated Con a Induced Growth Inhibition of 3T3 Cells in Tissue Culture.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 12 Cell Cycle Dependent Agglutinability, Distribution of Concanavalin a Binding Sites and Surface Morphology of Normal and Transformed Fibroblasts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 13 Concanavalin A and Other Lectins in the Study of Tumor Cell Surface Organization.- Abstract.- I. Introduction.- II. Methods.- III. Results.- IV. Discussion.- References.- 14 Modification of the Biological Activities of Concanavalin A by Anti-Concanavalin A.- Abstract.- I. Introduction.- II. Methods, Results, and Discussion.- References.- 15 Concanavalin A as A Probe for Studying the Mechanism of Metabolic Stimulation of Leukocytes.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 16 Enhanced Cytotoxicity in Mice of Combinations of Concanavalin A and Selected Antitumor Drugs.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- 17 Effect of Concanavalin A and Phytohemagglutinin on the Modification of Immunogenicity of Canine Kidney Allografts.- Abstract.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Discussion.- References.- Abstracts.- Evidence for Conformational Changes in Concanavalin A upon Binding of Saccharides as Determined from Solvent Water Proton Magnetic Relaxation Rate Dispersion Measurements.- Magnetic Resonance Studies of Concanavalin A: Location of The Binding Site of Methyl-D-Mannopyranoside.- The Metal Ion Requirements of Concanavalin A.- The Kinetics of Cellular Commitment during Stimulation of Lymphocytes by Concanavalin A.- Isolation of A Glycoprotein Receptor for Concanavalin A from the Outer Surface of Mouse L Cells.- Electron Microscopic Study on Interaction of Concanavalin A with Mouse Lymphosarcoma Cells in Tissue Culture and in Ascites form.- The Effect of Glutaraldehyde Fixation on the Agglutination of Human Erythrocytes by Concanavalin A and Soybean Agglutinin.- Altered Net Cation Transfer Across the Ehrlich Mouse Ascites Tumor Cell During Exposure to Concanavalin A.- Effects of Con A on Frog Nerve and Muscle.- Modification of the Surface Characteristics of Developing Hemopoietic Cells from Normal Human Bone Marrow Revealed Ultrastructurally by the Concanavalin A-Peroxidasediaminobenzidine Technique.- Effects of Succinyl-Con A on the Growth of Normal and Transformed Mouse Fibroblasts.- Endotoxin-Like Activities in Concanavalin A Preparations.- Concanavalin A Induced Inflammation.- Enhanced Immunogenicity of Con A Coated El-4 Leukemia Cells.- List of Contributors.

Key concepts: Concanavalin A, Chemistry, Function (biology), Glycoprotein, Membrane, Biophysics, Biochemistry, Biology

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