Evaluation of Antibacterial Activity of Flower Extracts of Cassia auriculata L.

Since plants are used as therapeutic agents, the present study was conducted to evaluate the phytochemical profile and antibacterial activities of flower extracts of Cassia auriculata. Studies on the antibacterial activity of ethanol, methanol and aqueous extracts of dry flower and ethanol, methanol and acetone extracts of fresh flower of Cassia auriculata was conducted using agar disc diffusion method. The microorganisms used include Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis, Salmonella typhi, Salmonella paratyphi A, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Vibrio cholerae and Shigella dysentrae. The maximum activity was observed against all organisms except Pseudomonas aeruginosa and Klebsiella pneumoniae. The minimum inhibitory concentration ranged between 12.5mg/mL and 75mg/mL depending on microorganism and various extract. Presence of phytochemicals such as terpenoids, tannins, flavonoids, saponin, cardiac glycosides and steroids were observed. Cassia auriculata was observed to have antibacterial activity and can be used for medicinal purposes.