2005Medical Entomology and ZoologyRequires access

Zinc finger proteins : from atomic contact to cellular function

史郎 井内, Natalie Kuldell

Open publisher page 83 citations

Abstract

Preface - Abbreviations- The Discovery of Zinc Fingers and Their Practical Applications in Gene Regulation - C2H2 Zinc Fingers As DNA Binding Domains - TFIIIA - GAGA- DNA Interaction - The DNA-Binding Domain of GATA Transcription Factors-A Prototypical Type IV Cys2-Cys2 Zinc Finger - MutM: Single C2C2 Zinc Finger-DNA Interaction - Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function -Zinc Finger Interactions with Metals and Other Small Molecules - Synthetic Zinc Finger Transcription Factors - TFIIIA and p43: Binding to 5S Ribosomal RNA - RNA Binding by Single Zinc Fingers - Wig-1, a p53-Induced Zinc Finger Protein that Binds Double Stranded RNA - Tandem CCCH Zinc Finger Proteins in mRNA Binding 80- Ribosomal Zinc Finger Proteins: The Structure and the Function of Yeast YL37a - LIM Domain and Its Binding to Target Proteins - RING Finger-B Box-Coiled Coil (RBCC) Proteins As Ubiquitin Ligase in the Control of Protein Degradation and Gene Regulation - Structure and Function of the CBP/p300 TAZ Domains - A Zinc Ribbon Motif Is Essential for the Formation of Functional Tetrameric Protein Kinase CK2 - The FYVE Finger: A Phosphoinositide Binding Domain - The BTB Domain Zinc Finger Proteins - KRAB Zinc Finger Proteins: A Family of Repressors Mediating Heterochromatin-Associated Gene Silencing - The Superfamily of SCAN Domain Containing Zinc Finger Transcription Factors - Sp1 and Huntington's Disease - The Role of WT1 in Development and Disease - Yin Yang 1 - The Multiple Cellular Functions of TFIIIA -The Role of the Ikaros Gene Family in Lymphocyte Development - Basonuclin: A Zinc Finger Protein of Epithelial Cells and Reproductive Germ Cells - ZAS Zinc Finger Proteins: The Other B-Binding Protein Family -Role of GATA Factors in Development -The Androgen Receptor and Spinal and Bulbar Muscular Atrophy - The Role of XPA in DNA Repair - MOF, an Acetyl Transferase Involved in Dosage Compensation in Drosophila, Uses a CCHC Finger forSubstrate Recognition - MDM2: RING Finger Protein and Regulator of p53 - The Zip Family of Zinc Transporters - Apoptosis by Zinc Deficiency -Index

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Preface - Abbreviations- The Discovery of Zinc Fingers and Their Practical Applications in Gene Regulation - C2H2 Zinc Fingers As DNA Binding Domains - TFIIIA - GAGA- DNA Interaction - The DNA-Binding Domain of GATA Transcription Factors-A Prototypical Type IV Cys2-Cys2 Zinc Finger - MutM: Single C2C2 Zinc Finger-DNA Interaction - Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function -Zinc Finger Interactions with Metals and Other Small Molecules - Synthetic Zinc Finger Transcription Factors - TFIIIA and p43: Binding to 5S Ribosomal RNA - RNA Binding by Single Zinc Fingers - Wig-1, a p53-Induced Zinc Finger Protein that Binds Double Stranded RNA - Tandem CCCH Zinc Finger Proteins in mRNA Binding 80- Ribosomal Zinc Finger Proteins: The Structure and the Function of Yeast YL37a - LIM Domain and Its Binding to Target Proteins - RING Finger-B Box-Coiled Coil (RBCC) Proteins As Ubiquitin Ligase in the Control of Protein Degradation and Gene Regulation - Structure and Function of the CBP/p300 TAZ Domains - A Zinc Ribbon Motif Is Essential for the Formation of Functional Tetrameric Protein Kinase CK2 - The FYVE Finger: A Phosphoinositide Binding Domain - The BTB Domain Zinc Finger Proteins - KRAB Zinc Finger Proteins: A Family of Repressors Mediating Heterochromatin-Associated Gene Silencing - The Superfamily of SCAN Domain Containing Zinc Finger Transcription Factors - Sp1 and Huntington's Disease - The Role of WT1 in Development and Disease - Yin Yang 1 - The Multiple Cellular Functions of TFIIIA -The Role of the Ikaros Gene Family in Lymphocyte Development - Basonuclin: A Zinc Finger Protein of Epithelial Cells and Reproductive Germ Cells - ZAS Zinc Finger Proteins: The Other B-Binding Protein Family -Role of GATA Factors in Development -The Androgen Receptor and Spinal and Bulbar Muscular Atrophy - The Role of XPA in DNA Repair - MOF, an Acetyl Transferase Involved in Dosage Compensation in Drosophila, Uses a CCHC Finger forSubstrate Recognition - MDM2: RING Finger Protein and Regulator of p53 - The Zip Family of Zinc Transporters - Apoptosis by Zinc Deficiency -Index

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Available abstract

Preface - Abbreviations- The Discovery of Zinc Fingers and Their Practical Applications in Gene Regulation - C2H2 Zinc Fingers As DNA Binding Domains - TFIIIA - GAGA- DNA Interaction - The DNA-Binding Domain of GATA Transcription Factors-A Prototypical Type IV Cys2-Cys2 Zinc Finger - MutM: Single C2C2 Zinc Finger-DNA Interaction - Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function -Zinc Finger Interactions with Metals and Other Small Molecules - Synthetic Zinc Finger Transcription Factors - TFIIIA and p43: Binding to 5S Ribosomal RNA - RNA Binding by Single Zinc Fingers - Wig-1, a p53-Induced Zinc Finger Protein that Binds Double Stranded RNA - Tandem CCCH Zinc Finger Proteins in mRNA Binding 80- Ribosomal Zinc Finger Proteins: The Structure and the Function of Yeast YL37a - LIM Domain and Its Binding to Target Proteins - RING Finger-B Box-Coiled Coil (RBCC) Proteins As Ubiquitin Ligase in the Control of Protein Degradation and Gene Regulation - Structure and Function of the CBP/p300 TAZ Domains - A Zinc Ribbon Motif Is Essential for the Formation of Functional Tetrameric Protein Kinase CK2 - The FYVE Finger: A Phosphoinositide Binding Domain - The BTB Domain Zinc Finger Proteins - KRAB Zinc Finger Proteins: A Family of Repressors Mediating Heterochromatin-Associated Gene Silencing - The Superfamily of SCAN Domain Containing Zinc Finger Transcription Factors - Sp1 and Huntington's Disease - The Role of WT1 in Development and Disease - Yin Yang 1 - The Multiple Cellular Functions of TFIIIA -The Role of the Ikaros Gene Family in Lymphocyte Development - Basonuclin: A Zinc Finger Protein of Epithelial Cells and Reproductive Germ Cells - ZAS Zinc Finger Proteins: The Other B-Binding Protein Family -Role of GATA Factors in Development -The Androgen Receptor and Spinal and Bulbar Muscular Atrophy - The Role of XPA in DNA Repair - MOF, an Acetyl Transferase Involved in Dosage Compensation in Drosophila, Uses a CCHC Finger forSubstrate Recognition - MDM2: RING Finger Protein and Regulator of p53 - The Zip Family of Zinc Transporters - Apoptosis by Zinc Deficiency -Index

Key concepts: Zinc finger, LIM domain, RING finger domain, Zinc finger nuclease, PHD finger, RNF4, Ring finger, Biology

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