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Phytochemical Screening and Antibacterial Activity of Leaf Extracts of Pterocarpus marsupium Roxb. (Fabaceae)

S. Ramya, M. Kalayansundaram, Kalaivani Thiagarajan, R. Jayakumararaj, Raja Duraisingam

Abstract

The present study was carried out to screen and evaluate the antimicrobial activity of bark and leaf extracts from Pterocarpus marsupium Roxb. Hexane, ethyl acetate and methanol extracts were tested against four selected Gram positive and Gram negative bacteria. Result indicated that phytochemical extracts of P. marsupium exhibited significant anti-bacterial activity at all dosage tested (1mg/ disc and 5mg/ disc). However, the inhibitory activity was found to be dose dependent. Ethyl acetate and methanol extracts were found to be more active towards the organisms tested than hexane extract. This study depicts that ethyl acetate and methanol extracts of bark and leaves of P. marsupium can be used as a potential source of novel antimicrobial agents.

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Key concepts: Phytochemical, Traditional medicine, Ethyl acetate, Bark (sound), Antimicrobial, Fabaceae, Antibacterial activity, Chemistry