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Mechanoreception by the vascular wall
Gabor M. Rubanyi
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Abstract
Biophysics of mechanotransduction Stretch-dependent myogenic tone in isolated blood vessels The myogenic response in microvascular networks The role of the myogenic response in autoregulation of blood flow Endothelial modulation of pressure-dependent myogenic vasoconstruction Pressure-induced vasoconstriction in isolated canine carotid areteries is mediated by suppression of EDRF release Pressure-induced vasoconstriction and membrane depolarisation is mediated by a diffusible endothelium-derived contracting factor in cat middle cerebral arteries Cytochrome P450 metabolites of arachidonic acid in the control of vascular tone Role of endothelium-derived nitric oxide in vasomotion Physical forces and angiogenesis.