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2009•Leprosy ReviewOpen access

Acute Generalized Exanthematous Pustulosis (AGEP) due to Dapsone in a patient with leprosy

P. Narasimharao, D. V. S. Pratap, Sujai Suneetha

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Abstract

Acute Generalized Exanthematous Pustulosis (AGEP) is a dermatosis characterised by an acute episode of appearance of sub-corneal sterile pustules over erythematous-edematous skin. AGEP is often associated with systemic symptoms such as high grade fever and is usually considered to be an adverse drug reaction, although a viral etiology is sometimes implicated. Here we report a case of AGEP following the intake of dapsone in a patient with leprosy.

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What this paper is about

Acute Generalized Exanthematous Pustulosis (AGEP) is a dermatosis characterised by an acute episode of appearance of sub-corneal sterile pustules over erythematous-edematous skin. AGEP is often associated with systemic symptoms such as high grade fever and is usually considered to be an adverse drug reaction, although a viral etiology is sometimes implicated. Here we report a case of AGEP following the intake of dapsone in a patient with leprosy.

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Available abstract

Acute Generalized Exanthematous Pustulosis (AGEP) is a dermatosis characterised by an acute episode of appearance of sub-corneal sterile pustules over erythematous-edematous skin. AGEP is often associated with systemic symptoms such as high grade fever and is usually considered to be an adverse drug reaction, although a viral etiology is sometimes implicated. Here we report a case of AGEP following the intake of dapsone in a patient with leprosy.

Key concepts: Acute generalized exanthematous pustulosis, Medicine, Leprosy, Dapsone, Dermatology

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