Effect of valproic acid and carbamazepine on learning and memory in rats
K. Rajesh, Surendra Rao, Thangam Joseph
Abstract
K. Rajesh, Surendra Rao, Thangam Joseph
Abstract
1. The effect of two antiepileptic agents valproic acid and carbamazepine was studied on learning and memory in rats. 2. Valproic acid in doses of 100, 200 & 400 mg/kg significantly inhibited learning and adversely affected memory retention. 3. Carbamazepine in the two doses studied 10 & 20 mg/kg significantly decreased learning but did not affect memory.
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1. The effect of two antiepileptic agents valproic acid and carbamazepine was studied on learning and memory in rats. 2. Valproic acid in doses of 100, 200 & 400 mg/kg significantly inhibited learning and adversely affected memory retention. 3. Carbamazepine in the two doses studied 10 & 20 mg/kg significantly decreased learning but did not affect memory.
Key concepts: Carbamazepine, Valproic Acid, Pharmacology, Chemistry, Anticonvulsant, Epilepsy, Medicine, Psychology