[Polymorphism of human mitochondrial DNA].
Marina Bermisheva, Tatiana V. Viktorova, Э. К. Хуснутдинова
Abstract
Marina Bermisheva, Tatiana V. Viktorova, Э. К. Хуснутдинова
Abstract
To date, a large data set on the mitochondrial DNA (mtDNA) sequence variation in human populations has been accumulated. The use of direct sequencing of the main noncoding region of mtDNA along with the RFLP analysis provide performance of complex analysis of mtDNA polymorphism in human populations. This approach proved to be effective for obtaining molecular genetic portraits of the world populations, as well as for the elucidation of the human evolutionary history and past migrations.
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To date, a large data set on the mitochondrial DNA (mtDNA) sequence variation in human populations has been accumulated. The use of direct sequencing of the main noncoding region of mtDNA along with the RFLP analysis provide performance of complex analysis of mtDNA polymorphism in human populations. This approach proved to be effective for obtaining molecular genetic portraits of the world populations, as well as for the elucidation of the human evolutionary history and past migrations.
Key concepts: Biology, Mitochondrial DNA, Human genetics, Genetics, Restriction fragment length polymorphism, Evolutionary biology, Human mitochondrial genetics, mtDNA control region