2024•Bio-Design and ManufacturingOpen access
Biofabrication and biomanufacturing in Ireland and the UK
Jack F. Murphy, Martha Lavelle, Lisa Asciak, Ross Burdis, Hannah J. Levis, Cosimo Ligorio, J.H. McGuire, Marlene Polleres, Poppy O. Smith, Lucinda Tullie, Juan Manuel Uribe, Biqiong Chen, Jonathan I. Dawson, Julien E. Gautrot, Nigel M. Hooper, Daniel J. Kelly, Vivian Li, Álvaro Mata, Abhay Pandit, James B. Phillips, Wenmiao Shu, Molly M. Stevens, Rachel Williams, James P. K. Armstrong, Yan Yan Shery Huang
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Abstract
As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering biology, sustainable manufacturing, and integrated design principles. Advanced techniques such as 3D bioprinting, tissue engineering, directed assembly, and self-assembly are instrumental in creating biomimetic scaffolds, tissues, organoids, medical devices, and biohybrid systems. The field of biofabrication in the United Kingdom and Ireland is emerging as a pivotal force in bioscience and healthcare, propelled by cutting-edge research and development. Concentrating on the production of biologically functional products for use in drug delivery, in vitro models, and tissue engineering, research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability, affordability, and healthcare system benefits.
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