2024•Gulhane Medical JournalOpen access

A rare occurrence of primary hyperparathyroidism with brown tumor in the left maxilla

Muhammad Afiq Muhammed Fahimy, Siti Rahmah Hashim Isa Merican, Maya Mazuwın Yahya, Muhamamad Faeid Othman

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Abstract

Brown tumors are rare skeletal manifestations of hyperparathyroidism. It is a form of osteitis fibrosa cystica caused by hyperparathyroidism due to excessive secretion of parathyroid hormone. Then, hypercalcemia results in excessive osteoclastic activity in the bones. Brown tumors are considered a rare complication of hyperparathyroidism, as their reported existence is only about 1.5-4.5%. Herein, we report a rare case of brown tumor arising from the left maxilla due to primary hyperparathyroidism, its challenge in diagnosis with giant cell tumor, and its literature review.

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What this paper is about

Brown tumors are rare skeletal manifestations of hyperparathyroidism. It is a form of osteitis fibrosa cystica caused by hyperparathyroidism due to excessive secretion of parathyroid hormone. Then, hypercalcemia results in excessive osteoclastic activity in the bones. Brown tumors are considered a rare complication of hyperparathyroidism, as their reported existence is only about 1.5-4.5%. Herein, we report a rare case of brown tumor arising from the left maxilla due to primary hyperparathyroidism, its challenge in diagnosis with giant cell tumor, and its literature review.

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Available abstract

Brown tumors are rare skeletal manifestations of hyperparathyroidism. It is a form of osteitis fibrosa cystica caused by hyperparathyroidism due to excessive secretion of parathyroid hormone. Then, hypercalcemia results in excessive osteoclastic activity in the bones. Brown tumors are considered a rare complication of hyperparathyroidism, as their reported existence is only about 1.5-4.5%. Herein, we report a rare case of brown tumor arising from the left maxilla due to primary hyperparathyroidism, its challenge in diagnosis with giant cell tumor, and its literature review.

Key concepts: Brown tumor, Medicine, Osteitis fibrosa cystica, Hyperparathyroidism, Osteitis, Primary hyperparathyroidism, Maxilla, Secondary hyperparathyroidism

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