2024•Global Journal of Health Sciences and ResearchOpen access

Sociodemographic features, serum urea, creatinine and blood urea nitrogen/creatinine ratio in chronic kidney disease patients – A record based retrospective study

H N Madhavan, M Nobel, M. Rajalakshmi, Shweta Kulkarni, Tresa Remya Athipozhi Thomas, B Shalini, Reenaa Mohan

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Abstract

Objectives: Chronic kidney disease (CKD) is a progressive reduction in renal function. It is a condition where the kidneys lose their normal function, especially excretory and regulatory functions. Urea and creatinine are good indicators of a normal functioning kidney and an increase in the serum indicates kidney dysfunction. Blood urea nitrogen (BUN) and serum creatinine are widely accepted and the most common parameters to assess renal functions. The present study was done to assess the serum urea, creatinine levels, and BUN-creatinine ratio (BCR) in CKD subjects. Material and Methods: It was a record-based retrospective study. Data were obtained from the Medical Records Department. The patients diagnosed with CKD in August 2023 were extracted from the records. Details such as hospital ID, age, gender, and blood parameters such as serum urea, creatinine levels, and BCR were obtained. Categorical data were summarized as frequency (percentage). Results: It was found that the number of male patients was 24 (75.4%) and the number of female patients was 14 (24.6%). The majority of patients belonging to the age group category of 50–75 were 42 in number (73.6%). Abnormal creatinine values were found in 54 patients (94.7%). Conclusion: The present study found that male gender and age group 50–75 years were most commonly affected with CKD. The serum creatinine level was found to be predominately abnormal compared to the serum urea level and BCR.

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Objectives: Chronic kidney disease (CKD) is a progressive reduction in renal function. It is a condition where the kidneys lose their normal function, especially excretory and regulatory functions. Urea and creatinine are good indicators of a normal functioning kidney and an increase in the serum indicates kidney dysfunction. Blood urea nitrogen (BUN) and serum creatinine are widely accepted and the most common parameters to assess renal functions. The present study was done to assess the serum urea, creatinine levels, and BUN-creatinine ratio (BCR) in CKD subjects. Material and Methods: It was a record-based retrospective study. Data were obtained from the Medical Records Department. The patients diagnosed with CKD in August 2023 were extracted from the records. Details such as hospital ID, age, gender, and blood parameters such as serum urea, creatinine levels, and BCR were obtained. Categorical data were summarized as frequency (percentage). Results: It was found that the number of male patients was 24 (75.4%) and the number of female patients was 14 (24.6%). The majority of patients belonging to the age group category of 50–75 were 42 in number (73.6%). Abnormal creatinine values were found in 54 patients (94.7%). Conclusion: The present study found that male gender and age group 50–75 years were most commonly affected with CKD. The serum creatinine level was found to be predominately abnormal compared to the serum urea level and BCR.

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Available abstract

Objectives: Chronic kidney disease (CKD) is a progressive reduction in renal function. It is a condition where the kidneys lose their normal function, especially excretory and regulatory functions. Urea and creatinine are good indicators of a normal functioning kidney and an increase in the serum indicates kidney dysfunction. Blood urea nitrogen (BUN) and serum creatinine are widely accepted and the most common parameters to assess renal functions. The present study was done to assess the serum urea, creatinine levels, and BUN-creatinine ratio (BCR) in CKD subjects. Material and Methods: It was a record-based retrospective study. Data were obtained from the Medical Records Department. The patients diagnosed with CKD in August 2023 were extracted from the records. Details such as hospital ID, age, gender, and blood parameters such as serum urea, creatinine levels, and BCR were obtained. Categorical data were summarized as frequency (percentage). Results: It was found that the number of male patients was 24 (75.4%) and the number of female patients was 14 (24.6%). The majority of patients belonging to the age group category of 50–75 were 42 in number (73.6%). Abnormal creatinine values were found in 54 patients (94.7%). Conclusion: The present study found that male gender and age group 50–75 years were most commonly affected with CKD. The serum creatinine level was found to be predominately abnormal compared to the serum urea level and BCR.

Key concepts: Creatinine, Blood urea nitrogen, Kidney disease, Urea, Urea nitrogen, Medicine, Urology, Internal medicine

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