Association of platelet satellitism with immune thrombocytopenia: A case report and review of literature

Platelet satellitism refers to the rosetting of the platelets around white blood cells, mostly neutrophils that could lead to spuriously low platelet counts on automated analyzers. The phenomenon has usually been described in EDTA processed blood samples. We describe the clinical course of a patient with immune thrombocytopenia with platelet satellitism in both EDTA as well as non EDTA processed blood samples. We also review the literature describing two other reports of the platelet satellitism in patients with immune thrombocytopenia. We also reference the literature describing the heterogeneity of the presence of platelet satellitism in different clinical and laboratory settings.