2024•Natural Product ReportsOpen access

Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains

Stephanie C. Heard, Jaclyn M. Winter

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Abstract

This review highlights the utility of using adenylation domain structural data, biochemical assays, and computational predictions for prioritizing nonribosomal peptide pathways for natural product discovery.

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This review highlights the utility of using adenylation domain structural data, biochemical assays, and computational predictions for prioritizing nonribosomal peptide pathways for natural product discovery.

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OpenAlex reports 37 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This review highlights the utility of using adenylation domain structural data, biochemical assays, and computational predictions for prioritizing nonribosomal peptide pathways for natural product discovery.

Key concepts: Nonribosomal peptide, Adenylylation, Natural product, Computational biology, Peptide, Biology, Domain (mathematical analysis), Biochemistry

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Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains — Research Paper | ScholarLens