Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains
Stephanie C. Heard, Jaclyn M. Winter
Abstract
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Stephanie C. Heard, Jaclyn M. Winter
Abstract
Open-access reader
This review highlights the utility of using adenylation domain structural data, biochemical assays, and computational predictions for prioritizing nonribosomal peptide pathways for natural product discovery.
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This review highlights the utility of using adenylation domain structural data, biochemical assays, and computational predictions for prioritizing nonribosomal peptide pathways for natural product discovery.
Key concepts: Nonribosomal peptide, Adenylylation, Natural product, Computational biology, Peptide, Biology, Domain (mathematical analysis), Biochemistry