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2023•Biomedical Research and TherapyOpen access

Severe Hemolysis Triggered by Favism in a Female Patient with G6PD Deficiency: A Case Report

Nabilah Rameli, Justin Hor Hung Juan, Ling Pei, Nurul Akbar, Adibah Daud, Syamihah Mardhiah A. Razak, Sumaiyah Adzahar

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Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary enzymatic disorder that can result in acute hemolytic anemia under certain conditions. Favism, induced by ingesting fava beans, is a well-known trigger of hemolysis in individuals with G6PD deficiency. We report the case of a five-year-old girl who presented to our hospital with signs and symptoms of hemolysis. At admission, we were unaware that she had an underlying G6PD deficiency and detected it while performing laboratory investigations to determine the etiology.

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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary enzymatic disorder that can result in acute hemolytic anemia under certain conditions. Favism, induced by ingesting fava beans, is a well-known trigger of hemolysis in individuals with G6PD deficiency. We report the case of a five-year-old girl who presented to our hospital with signs and symptoms of hemolysis. At admission, we were unaware that she had an underlying G6PD deficiency and detected it while performing laboratory investigations to determine the etiology.

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Available abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary enzymatic disorder that can result in acute hemolytic anemia under certain conditions. Favism, induced by ingesting fava beans, is a well-known trigger of hemolysis in individuals with G6PD deficiency. We report the case of a five-year-old girl who presented to our hospital with signs and symptoms of hemolysis. At admission, we were unaware that she had an underlying G6PD deficiency and detected it while performing laboratory investigations to determine the etiology.

Key concepts: Hemolysis, Medicine, Glucose-6-phosphate dehydrogenase deficiency, Glucosephosphate Dehydrogenase Deficiency, Hemolytic anemia, Glucose-6-phosphate dehydrogenase, Etiology, Enzyme deficiency

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