Cortical dysplasias

Abstract Classification based on Dobyns and Truwit (1995). Lissencephaly (agyria/pachygyria diffuse with abnormally thick cortex and only four layers). Also called lissencephaly type 1: classical: Miller-Dieker syndrome; Lissencephaly sequence; lissencephaly with very small head including a small cerebellum; Cobblestone lissencephaly or lissencephaly type II (a mixture of agyria, pachygyria and polymicrogyria, enlarged ventricles, small brainstem, cerebellun, especially vermis and cerebellar polymicrogyria): Hydrocephalus, agyria, retinal dysplasia (HARD) (seep. 56); the congenital muscular dystrophies (seep. 218);