2023•Internal MedicineOpen access
An Autopsy Case of Post-COVID-19 Interstitial Lung Disease with Acute Exacerbation
Akifumi Tsuzuku, Fumihiro Asano, Masaki Katayama, Kosuke Mori, Yui Sasaki, Yutaro Kuzunishi, Mayuka Taguchi, Yuya Muto, Yasutomo Baba, Akimasa Tsuchida, Tomoya Kato, Anri Murakami, Atsunori Masuda, Takashi Yoshizane, Jun Suzuki
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Abstract
The prognosis of patients with post-coronavirus disease 2019 (COVID-19) interstitial lung disease remains unclear. We herein report an autopsy case in which serial progression after the onset of post-COVID-19 interstitial lung disease resulted in an acute exacerbation, leading to a fatal outcome. Autopsy findings included hyaline membrane formation/interstitial inflammatory cell infiltration, suggestive of acute lesions, and severe regional fibrosis, indicating a preexisting chronic condition. In the present case, we histopathologically confirmed the acute exacerbation of post-COVID-19 interstitial lung disease.
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