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Cubane and Cyclooctatetraene Used as Bioisosteres in Drug Development

Dirk H. Trauner, Xiang Ji

Abstract

Key words cubane - cyclooctatetraene (COT) - idiopathic pulmonary fibrosis (IPF) - bioisostere replacement Publication History Article published online: 14 September 2023 © 2023. Thieme. All rights reserved Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

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Available abstract

Key concepts: Cyclooctatetraene, Bioisostere, Cubane, Chemistry, Key (lock), Stereochemistry, Crystallography, Molecule

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