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2023•PhytomedicineRequires access

Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii

Manyun Dai, Peng Wan, Lisha Lin, Zhanxuan E. Wu, Ting Zhang, Qi Zhao, Yan Cheng, Qiuxia Lin, Binbin Zhang, Aiming Liu, Qianru Rao, Jianfeng Huang, Jinhua Zhao, Frank J. Gonzalez, Fei Li

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Key concepts: Celastrol, Triptolide, Tripterygium wilfordii, Tripterygium, Farnesoid X receptor, Pharmacology, Chemistry, Downregulation and upregulation

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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii — Research Paper | ScholarLens