2023•World Journal of DentistryOpen access

Calprotectin, S100A8, and S100A9: Potential Biomarkers of Periodontal Inflammation: A Scoping Review

Sukumaran Anil, Sankari Malaiappan, Annie George, Betsy Joseph

Abstract

Calprotectin has an antimicrobial role in its metal-binding structure.Each of the homodimers, S1008, and S100A9, have two EF hand-type Ca + binding sites.Calprotectin plays a key role in innate immune responses and binds to metal ions such as zinc, iron, and manganese, depriving bacteria of their nutritional requirements.8

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Key concepts: Calprotectin, S100A8, S100A9, Inflammation, Medicine, Internal medicine, Inflammatory bowel disease, Disease