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2023•International Journal of Science and Research ArchiveOpen access

Piperacillin-tazobactam induced thrombocytopenia: A case report

Nikhil M Sunny, Neha Susan Vinu, Sumith K. Mathew

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Abstract

Piperacillin-tazobactam is a commonly used antibiotic that belongs to penicillin and beta-lactam inhibitors, which has a wide range of gram-negative bacteria and limited gram-positive activity. This case report presents one of the rare ADR of piperacillin–tazobactam –thrombocytopenia where a dramatic improvement within 24hrs in platelet count was observed after withdrawing the drug. Few cases of piperacillin tazobactam-induced thrombocytopenia have been reported.

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Piperacillin-tazobactam is a commonly used antibiotic that belongs to penicillin and beta-lactam inhibitors, which has a wide range of gram-negative bacteria and limited gram-positive activity. This case report presents one of the rare ADR of piperacillin–tazobactam –thrombocytopenia where a dramatic improvement within 24hrs in platelet count was observed after withdrawing the drug. Few cases of piperacillin tazobactam-induced thrombocytopenia have been reported.

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Available abstract

Piperacillin-tazobactam is a commonly used antibiotic that belongs to penicillin and beta-lactam inhibitors, which has a wide range of gram-negative bacteria and limited gram-positive activity. This case report presents one of the rare ADR of piperacillin–tazobactam –thrombocytopenia where a dramatic improvement within 24hrs in platelet count was observed after withdrawing the drug. Few cases of piperacillin tazobactam-induced thrombocytopenia have been reported.

Key concepts: Piperacillin/tazobactam, Piperacillin, Tazobactam, Penicillin, Medicine, Antibiotics, Platelet, Beta-Lactamase Inhibitors

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