2011•Педиатрическая фармакологияOpen access
Современные возможности иммунопрофилактики тяжелого течения респираторно-синцитиальной вирусной инфекции у детей с последствиями перинатальной патологии
Leyla Seymurovna Namazova-Baranova, Irina V. Davydova, Tatiana V. Turti, И.А. Беляева, В. В. Алтунин
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Abstract
To a risk group of a heavy course of the respiratory syncytial viral (RSV) infection could be ascribed preterm infants, born before the 35 t h week of gestation inclusive, as well as children under 2 years old with the bronchopulmonary dysplasia or hemodynamically significant congenital heart defects. World experience shows that the seasonal immunoprophylaxis against RSV-infection with palivizumab in these patients enables to reduce the frequency of hospitalization and resuscitation measures, as well as to decrease the number of deaths. The article presents authors’ clinical and laboratory data and instrumental evaluation of the efficacy and safety of palivizumab on specific clinical examples. Key words: respiratory syncytial virus, acute respiratory viral infection, prematurity, bronchopulmonary dysplasia, congenital heart defects, palivizumab.