2023RSC AdvancesOpen access

Design, synthesis and evaluation of a myricetin and nobiletin hybrid compound for alleviating hyperuricemia based on metabolomics and gut microbiota

Yan Li, Liu‐Yang Pu, Yayun Li, Guanbao Zhu, Zhengzhi Wu

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Abstract

A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.

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A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.

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Available abstract

A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.

Key concepts: Myricetin, Nobiletin, Hyperuricemia, Metabolomics, Gut flora, Chemistry, Uric acid, Quercetin

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Design, synthesis and evaluation of a myricetin and nobiletin hybrid compound for alleviating hyperuricemia based on metabolomics and gut microbiota — Research Paper | ScholarLens