Design, synthesis and evaluation of a myricetin and nobiletin hybrid compound for alleviating hyperuricemia based on metabolomics and gut microbiota
Yan Li, Liu‐Yang Pu, Yayun Li, Guanbao Zhu, Zhengzhi Wu
Abstract
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Yan Li, Liu‐Yang Pu, Yayun Li, Guanbao Zhu, Zhengzhi Wu
Abstract
Open-access reader
A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.
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A hybrid compound consisting of myricetin and nobiletin (MNH) was designed and synthesized, which might represent a protective effect against HUA via modulating the gut microbiota composition and serum metabolite profile.
Key concepts: Myricetin, Nobiletin, Hyperuricemia, Metabolomics, Gut flora, Chemistry, Uric acid, Quercetin