Detection of antisperm antibodies in patients with unexplained infertility

Objective: To detect Antisperm antibodies in Patient’s with unexplained infertility. Method: This study was undertaken in 50 patient of unexplained infertility who were admitted in the indoor ward and those attending outpatient Department of obs and Gynae of M.L.N Medical College, Prayagraj. fifty couples with no organic cause for infertility were selected for this study.25.58% of couples with primary unexplained infertility showed positive ASA while only 14.42% of couples with secondary unexplained infertility showed positive results.No correlation was present between the presence of ASA and duration of infertility,socio economic status and ethnic group. Result: Antisperm antibody has a high predictive value for the patient with unexplained infertility. Presence of antisperm antibody was a more accurate predictor of Unexplained infertility than other historical risk factors. The serological test is rapid and non-invasive, and our data suggests that it would be useful in investigation of infertility. Conclusion: Antisperm antibody is a Sensitive, specific, easy, non-invasive and reliable test for diagnosis of Unexplained infertility