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2022•PubMedOpen access

Porphyromonas Gingivalis in the Development of Periodontitis: Impact on Dysbiosis and Inflammation.

Asma Gasmi Benahmed, Pavan Kumar Mujawdiya, Sàdaf Noor, Amin Gasmi

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Abstract

. Its presence in the periodontal tissues increases the secretion of numerous pro-inflammatory mediators such as TNF-α, IL-8, and IL-1β, leading to the destruction of soft gingival tissues and ligaments. Early detection of periodontitis and immediate treatment can prevent soft tissue destruction and dentition loss. In conclusion, details about the oral microbiome, oral dysbiosis, and inflammation may offer new therapeutic options in the future, including a personalized approach and the use of combination therapy.

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. Its presence in the periodontal tissues increases the secretion of numerous pro-inflammatory mediators such as TNF-α, IL-8, and IL-1β, leading to the destruction of soft gingival tissues and ligaments. Early detection of periodontitis and immediate treatment can prevent soft tissue destruction and dentition loss. In conclusion, details about the oral microbiome, oral dysbiosis, and inflammation may offer new therapeutic options in the future, including a personalized approach and the use of combination therapy.

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Available abstract

. Its presence in the periodontal tissues increases the secretion of numerous pro-inflammatory mediators such as TNF-α, IL-8, and IL-1β, leading to the destruction of soft gingival tissues and ligaments. Early detection of periodontitis and immediate treatment can prevent soft tissue destruction and dentition loss. In conclusion, details about the oral microbiome, oral dysbiosis, and inflammation may offer new therapeutic options in the future, including a personalized approach and the use of combination therapy.

Key concepts: Porphyromonas gingivalis, Periodontitis, Dysbiosis, Microbiology, Fusobacterium nucleatum, Medicine, Aggregatibacter actinomycetemcomitans, Immunology

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Porphyromonas Gingivalis in the Development of Periodontitis: Impact on Dysbiosis and Inflammation. — Research Paper | ScholarLens