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2023•Unpublished venueOpen access

Author response: Optimal cancer evasion in a dynamic immune microenvironment generates diverse post-escape tumor antigenicity profiles

Jason T. George, Herbert Levine

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Abstract

Theoretical modeling reveals how stochastic optimal cancer immune evasion via antigen downregulation gives rise to diverse post-escape cancer antigenic profiles in a manner dependent on the immune microenvironment.

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What this paper is about

Theoretical modeling reveals how stochastic optimal cancer immune evasion via antigen downregulation gives rise to diverse post-escape cancer antigenic profiles in a manner dependent on the immune microenvironment.

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Available abstract

Theoretical modeling reveals how stochastic optimal cancer immune evasion via antigen downregulation gives rise to diverse post-escape cancer antigenic profiles in a manner dependent on the immune microenvironment.

Key concepts: Evasion (ethics), Immune escape, Antigenicity, Immune system, Tumor microenvironment, Biology, Cancer, Computational biology

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