2023•International Journal of Advanced ResearchOpen access

SKULL BASE CHORDOMA: ABOUT TWO CASES AND LITERATUREREVIEW

Karima Nouni, H. Benmessaoud, Imane Mbarki, S. ElMajjaoui, H. Elkacemi, T. Kebdani, K. Hassouni

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Abstract

Skull base chordomasare rare primitive bone tumors developed at the expense of remnants of the embryonic notochord at the level of the clivus, characterized by invasive behavior at the local levelwithpossibility of extension to neighbouringorgans. The deep localization of these tumors and their proximity to the structures of the base of the skull round a carcinological resection difficult if not impossible. Radiation therapy, both adjuvant to surgery and exclusive, is a therapeutic approach to improve local control and quality of life for patients. Wepresenttwocases of patients followed for skull base chordomatreatedwith exclusive radiotherapy.

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What this paper is about

Skull base chordomasare rare primitive bone tumors developed at the expense of remnants of the embryonic notochord at the level of the clivus, characterized by invasive behavior at the local levelwithpossibility of extension to neighbouringorgans. The deep localization of these tumors and their proximity to the structures of the base of the skull round a carcinological resection difficult if not impossible. Radiation therapy, both adjuvant to surgery and exclusive, is a therapeutic approach to improve local control and quality of life for patients. Wepresenttwocases of patients followed for skull base chordomatreatedwith exclusive radiotherapy.

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Available abstract

Skull base chordomasare rare primitive bone tumors developed at the expense of remnants of the embryonic notochord at the level of the clivus, characterized by invasive behavior at the local levelwithpossibility of extension to neighbouringorgans. The deep localization of these tumors and their proximity to the structures of the base of the skull round a carcinological resection difficult if not impossible. Radiation therapy, both adjuvant to surgery and exclusive, is a therapeutic approach to improve local control and quality of life for patients. Wepresenttwocases of patients followed for skull base chordomatreatedwith exclusive radiotherapy.

Key concepts: Clivus, Skull, Chordoma, Radiation therapy, Notochord, Anatomy, Medicine, Surgery

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