2023•Unpublished venueOpen access

Effect of the complex on human fibroblast cell line. from Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity

Mariangela Garofalo, Barbara Iovine, Łukasz Kuryk, Cristian Capasso, Mari Hirvinen, Andrea Vitale, Marjo L. Yliperttula, Maria Assunta Bevilacqua, Vincenzo Cerullo

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Abstract

Most representative microscop photograph of human fibroblast cell line. (E) Cell viability was performed by MTS Assay on CCD- 112Sk cell line, in order to evaluate if complex affects negatively healthy cells. We have not observed toxic effect(incubation time 96 hrs) on fibroblast cultures, neither with complex nor virus alone and Carnosine6K alone (virus:100 VP/cell, Carnosine6K: 8mM).

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Most representative microscop photograph of human fibroblast cell line. (E) Cell viability was performed by MTS Assay on CCD- 112Sk cell line, in order to evaluate if complex affects negatively healthy cells. We have not observed toxic effect(incubation time 96 hrs) on fibroblast cultures, neither with complex nor virus alone and Carnosine6K alone (virus:100 VP/cell, Carnosine6K: 8mM).

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Available abstract

Most representative microscop photograph of human fibroblast cell line. (E) Cell viability was performed by MTS Assay on CCD- 112Sk cell line, in order to evaluate if complex affects negatively healthy cells. We have not observed toxic effect(incubation time 96 hrs) on fibroblast cultures, neither with complex nor virus alone and Carnosine6K alone (virus:100 VP/cell, Carnosine6K: 8mM).

Key concepts: Fibroblast, Oncolytic virus, Cell culture, Cell, Viability assay, Incubation, Virus, Molecular biology

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Effect of the complex on human fibroblast cell line. from Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity — Research Paper | ScholarLens