2023•Unpublished venueOpen access

Supplementary Figure 1 from SRC Signaling Is Crucial in the Growth of Synovial Sarcoma Cells

Sebastian Yves Friedrich Michels, Marcel Trautmann, Elisabeth Sievers, Dagmar Kindler, Sebastian Huss, Marcus Renner, Nicolaus Friedrichs, Jutta Kirfel, Susanne Steiner, Elmar Endl, Peter Wurst, Lukas Carl Heukamp, Roland Penzel, Olle Larsson, Akira Kawai, Shinya Tanaka, Hiroshi Sonobe, Peter Schirmacher, Gunhild Mechtersheimer, Eva Wardelmann, Reinhard Büttner, Wolfgang Hartmann

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Abstract

PDF file - 70K, As an indirect proof of specific SRC-related action of dasatinib in synovial sarcoma cells, CME-1 did not display any significant effects upon dasatinib treatement after siRNA-mediated SRC-knockdown.

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Key concepts: Dasatinib, Proto-oncogene tyrosine-protein kinase Src, Synovial sarcoma, Gene knockdown, Sarcoma, Cancer research, Chemistry, Medicine