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2023•Bioorganic & Medicinal Chemistry LettersRequires access

Synthesis of oligonucleotides containing 5′-homo-4′-selenouridine derivative and its increased resistance against nuclease

Jinha Yu, Ji Won Kim, Girish Chandra, Noriko Saito–Tarashima, Yuhei Nogi, Masashi Ota, Noriaki Minakawa, Lak Shin Jeong

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Key concepts: Oligonucleotide, Nuclease, Chemistry, Thermal stability, Monomer, Chemical stability, Chemical modification, DNA

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Synthesis of oligonucleotides containing 5′-homo-4′-selenouridine derivative and its increased resistance against nuclease — Research Paper | ScholarLens