Comparison the Level of the IL-20 Cytokine in Gingival Crevicular Fluid in Periodontally Health and Periodontitis Patients

Background: Periodontitis refer to the inflammation of the tissues surrounding tooth structure. Multiple cytokines are involved in the pathogenesis of periodontitis. Objectives: A comparison of the IL-20 level found in gingival crevicular fluid in healthy and periodontitis patients. Methods: GCF samples were obtained from both patients systematic healthy with periodontitis and with healthy periodontium patients. The subjects included in this study were divided into two equal groups: group 1: included 10 patients with stage 3-4 periodontitis and group 2: included 10 periodontally healthy subjects. The GCF samples were collected. All samples were stored at -80°C till laboratory analysis. IL-20 levels were measured by ELISA. Results: IL-20 levels were significantly higher in patients with Periodontitis compared with healthy periodontal patients (p-value ≤ 0.05) Conclusions: IL -20 play a role in Periodontitis patients. Key words: IL-20, Periodontitis Patient, GCF