Medicinal Plant Extraction of Zingiber Officinale Rhizome using Response Surface Methodology (RSM) and Characterization of the Product

Abstract Ginger oleoresin is a valuable product with functional health benefits. Oleoresin has components in the form of volatile and non-volatile substances that are very easy to decompose. One of the essential components and easy-to-decompose compound is gingerol, which has improved functionality and is effective in enhancing immunity in herds of bodies. Oleoresin is a ginger rhizome extraction product full of active ingredients that may be utilized as medicines. Ginger oleoresin extract has a pale yellow, oily fat, and a unique and spicy odor. Gingerol is one of the compounds in ginger oleoresin that is easily decomposed into another substance. Gingerol (C 17 H 26 O 4 ) is an easy compound to decompose into Shogaols (C 17 H 24 O 3 ). Both of these compounds, whether gingerol or shogaol, have health benefits in the body, such as antioxidant, antimicrobial, anti-inflammatory, anti-allergic, and anti-cancer. The aim of the research is an initial study on the preparation of oleoresin extract with ethanol solvent using the Response Surface Method (RSM) with a three-factor experimental and two responses (yield and [6]-gingerol content). A maximum oleoresin extract yield of 7.44 % and [6]-gingerol content of 11.71% was obtained from the experimental design. The extraction of zingiber rhizomes powder was processed under the best condition at a solvent ratio (S/L) of 6.577, a temperature of 58.87°C, and the extraction process lasted 182 minutes.