2022HPU2 Journal of Science Natural Sciences and TechnologyOpen access

Some notes on the dynamic behavior of COVID-19 epidemic disease governed by modified SEIR epidemic model with saturated treatment function

Thanh-Dung Dao, Van-Huy Kieu, Hong-Ngat Kieu Thi, Chi-Nguyen Nguyen

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Abstract

In this work, based on theory of differential systems and stability theory, we are in the first stage to study some applications of differential systems in real-world modelling problems. Here, we propose a mathematical epidemic model, namely SEIR epidemic model with saturated treatment to describe the COVID-19 infection. Based on the next–generation matrix method and the theory of Lyapunov stability, we evaluate the basic reproduction number and investigate the asymptotic behavior of disease-free equilibrium. Additionally, in the case , we also prove the existence of a unique endemic equilibrium. Finally, in order to dicuss the effect of isolation control strategies, we study the optimal control problem for this epidemic model.

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What this paper is about

In this work, based on theory of differential systems and stability theory, we are in the first stage to study some applications of differential systems in real-world modelling problems. Here, we propose a mathematical epidemic model, namely SEIR epidemic model with saturated treatment to describe the COVID-19 infection. Based on the next–generation matrix method and the theory of Lyapunov stability, we evaluate the basic reproduction number and investigate the asymptotic behavior of disease-free equilibrium. Additionally, in the case , we also prove the existence of a unique endemic equilibrium. Finally, in order to dicuss the effect of isolation control strategies, we study the optimal control problem for this epidemic model.

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Available abstract

In this work, based on theory of differential systems and stability theory, we are in the first stage to study some applications of differential systems in real-world modelling problems. Here, we propose a mathematical epidemic model, namely SEIR epidemic model with saturated treatment to describe the COVID-19 infection. Based on the next–generation matrix method and the theory of Lyapunov stability, we evaluate the basic reproduction number and investigate the asymptotic behavior of disease-free equilibrium. Additionally, in the case , we also prove the existence of a unique endemic equilibrium. Finally, in order to dicuss the effect of isolation control strategies, we study the optimal control problem for this epidemic model.

Key concepts: Epidemic model, Basic reproduction number, Lyapunov function, Coronavirus disease 2019 (COVID-19), Epidemic disease, Stability (learning theory), Applied mathematics, Exponential stability

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