Manipulation of micro/nano particles by combining acoustic radiation force with acoustic streaming

In this study, we propose a manipulation method of micro/nano particles based on an acoustic radiation force and an acoustic streaming. In recent years, analyses of micro/nano particles are attracting large attention in the fields of medicine or biology. In a manipulation of micro/nano particles, acoustofluidics is a strong candidate because of its high throughput, low invasiveness and simple systems. Manipulation methods based on acoustofluidics consist of acoustic radiation force and acoustic streaming. Acoustic radiation force can arrange microparticles with high precision. On the other hand, acoustic streaming can manipulate nanoparticles with strong force. Thus, we can manipulate both micro and nano particles by combining acoustic radiation force and acoustic streaming. In this study, we fabricated a device to manipulate micro/nano particles by combining acoustic radiation force and acoustic streaming. As a result, we manipulated micro particles by using acoustic radiation force and we observed acoustic streaming were generated.