2022•Journal of Cancer TherapyOpen access

Unilateral Ptosis in a Child with Wilm’s Tumor Induced by Vincristine

Aziza El Ouali, Karim Lahrache, Zohair El Haddar, Ayad Ghannam, Abdeladim Babakhouya, Maria Rkain, Noufissa Benajiba

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Abstract

Vincristine is a chemotherapy drug belonging to the group of Vinca alkaloids which also includes vinblastine and vindesine. It is used in hematological malignancies and solid tumors. The Vinca alkaloids are neurotoxic, usually causing peripheral neuropathy, and rarely cranial neuropathies. We report a case of a 33-month-old male child diagnosed with Wilms’ tumor, who had an isolated unilateral right ptosis following vincristine, with a good improvement after stopping it.

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Vincristine is a chemotherapy drug belonging to the group of Vinca alkaloids which also includes vinblastine and vindesine. It is used in hematological malignancies and solid tumors. The Vinca alkaloids are neurotoxic, usually causing peripheral neuropathy, and rarely cranial neuropathies. We report a case of a 33-month-old male child diagnosed with Wilms’ tumor, who had an isolated unilateral right ptosis following vincristine, with a good improvement after stopping it.

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Available abstract

Vincristine is a chemotherapy drug belonging to the group of Vinca alkaloids which also includes vinblastine and vindesine. It is used in hematological malignancies and solid tumors. The Vinca alkaloids are neurotoxic, usually causing peripheral neuropathy, and rarely cranial neuropathies. We report a case of a 33-month-old male child diagnosed with Wilms’ tumor, who had an isolated unilateral right ptosis following vincristine, with a good improvement after stopping it.

Key concepts: Vinca, Vindesine, Vincristine, Vinblastine, Ptosis, Medicine, Chemotherapy, Surgery

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Unilateral Ptosis in a Child with Wilm’s Tumor Induced by Vincristine — Research Paper | ScholarLens