Molecular Mechanisms to Target Cellular Senescence in Aging and Disease
Serena Marcozzi, Antonio Paolo Beltrami, Marco Malavolta
Abstract
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Serena Marcozzi, Antonio Paolo Beltrami, Marco Malavolta
Abstract
Open-access reader
Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].
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Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].
Key concepts: Telomere, Cellular Aging, Senescence, Cellular senescence, Epigenetics, Cell biology, DNA damage, Biology