2022CellsOpen access

Molecular Mechanisms to Target Cellular Senescence in Aging and Disease

Serena Marcozzi, Antonio Paolo Beltrami, Marco Malavolta

Open full text 18 citations

Abstract

Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].

Open-access reader

About this research paper

What this paper is about

Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].

Why it matters

OpenAlex reports 18 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, including DNA damage, increased cellular oxidative stress, telomere shortening, oncogene activation, and a deep epigenetic remodeling [...].

Key concepts: Telomere, Cellular Aging, Senescence, Cellular senescence, Epigenetics, Cell biology, DNA damage, Biology

Related papers

Back to paper searchBrowse research topicsOriginal source
Molecular Mechanisms to Target Cellular Senescence in Aging and Disease — Research Paper | ScholarLens