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2022•International Journal of Cardiovascular PracticeOpen access

Methadone-Induced QT Interval Prolongation and Torsades de Pointes

Shiva Tabaghi, Mohammad Ali Akbarzadeh

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Abstract

: The most common cause of acquired long QT syndrome in patients without physiological and structural cardiovascular disease is the use of medications. Chronic high-dose methadone usage can cause prolongation of QT interval that may provoke the life-threatening arrhythmia Torsades de Pointes. In this study, we present a 41-year-old man with chronic high-dose methadone usage who developed Torsades de Pointes triggered by short-coupled premature ventricular contraction.

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: The most common cause of acquired long QT syndrome in patients without physiological and structural cardiovascular disease is the use of medications. Chronic high-dose methadone usage can cause prolongation of QT interval that may provoke the life-threatening arrhythmia Torsades de Pointes. In this study, we present a 41-year-old man with chronic high-dose methadone usage who developed Torsades de Pointes triggered by short-coupled premature ventricular contraction.

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Available abstract

: The most common cause of acquired long QT syndrome in patients without physiological and structural cardiovascular disease is the use of medications. Chronic high-dose methadone usage can cause prolongation of QT interval that may provoke the life-threatening arrhythmia Torsades de Pointes. In this study, we present a 41-year-old man with chronic high-dose methadone usage who developed Torsades de Pointes triggered by short-coupled premature ventricular contraction.

Key concepts: Torsades de pointes, QT interval, Prolongation, Medicine, Methadone, Long QT syndrome, Cardiology, Anesthesia

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