1982Journal of Forensic SciencesRequires access

Hydromorphone Detected in Bile Following Hydrocodone Ingestion

J. I. Park, G. R. Nakamura, Ernest C. Griesemer, TT Noguchi

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Abstract

Abstract Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.

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What this paper is about

Abstract Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.

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Available abstract

Abstract Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.

Key concepts: Hydrocodone, Hydromorphone, Ingestion, Medicine, Poison control, Emergency medicine, Internal medicine, Oxycodone

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