Hydromorphone Detected in Bile Following Hydrocodone Ingestion
J. I. Park, G. R. Nakamura, Ernest C. Griesemer, TT Noguchi
Abstract
J. I. Park, G. R. Nakamura, Ernest C. Griesemer, TT Noguchi
Abstract
Abstract Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.
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Abstract Two similar cases are reported here in which Tussionex® a preparation containing hydrocodone and phenyltoloxamine, caused or contributed to death. Toxicological analyses revealed a high concentration ratio of hydromorphone to hydrocodone in the bile in both cases. It is postulated that the finding of hydromorphone is due to the metabolism of hydrocodone.
Key concepts: Hydrocodone, Hydromorphone, Ingestion, Medicine, Poison control, Emergency medicine, Internal medicine, Oxycodone