Pasireotide (SIGNIFOR) in acromegaly. After treatment failure: better than pegvisomant.
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Abstract
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Abstract
In a trial including 198 patients in whom several lines of treatments had failed, pasireotide normalised IGF-1 and GH levels and sometimes reduced the size of the pituitary adenoma, but often at a cost of developing diabetes.
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In a trial including 198 patients in whom several lines of treatments had failed, pasireotide normalised IGF-1 and GH levels and sometimes reduced the size of the pituitary adenoma, but often at a cost of developing diabetes.
Key concepts: Acromegaly, Pasireotide, Pegvisomant, Medicine, Pituitary adenoma, Internal medicine, Diabetes mellitus, Endocrinology