1994•Journal of Electron MicroscopyRequires access
Electron Microscopic Cytochemistry of Acid Phosphatase Activity in Dystrophic Axons of Rat Gracile Nuclei
Ikuo Takeuchi, Eiko Aoki, Yoshiko Takeuchi
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Abstract
Dystrophic axons (DAs) in rat gracile nuclei were largely classified into two types. One type had a focal swelling measuring about 2–8 μm in diameter, and contained greatly increased numbers of various cellular organdies. Numerous reaction products of acid phosphatase (ACPase) cytochemistry were deposited in the cytoplasmic matrix and the mulnlaminated bodies. The second type ranged from 8 μm to 50 μm in diameter, and was characterized by the presence of a large number of fine tubular structures in the cytoplasm. Only a few reaction products of ACPase cytochemistry were localized in the small vesicular structures. The functional role of ACPase in the degradation and accumulation of cellular organdies in DAs is discussed.