2020•Carolina Digital Repository (University of North Carolina at Chapel Hill)Open access
Conjugated Equine Estrogen Influence on Mammographic Density in Postmenopausal Women in a Substudy of the Women's Health Initiative Randomized Trial
Rowan T. Chlebowski, Etta D. Pisano, Karen Johnson, Robert B. Wallace, Jennifer D. Peck, C.Y. Wang, Mara Z. Vitolins, Christopher B. Martin, JoAnn E. Manson, Gerardo M HEISS, Anne McTiernan, Aaron K. Aragaki
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Abstract
Increased mammographic density is associated with increased breast cancer risk and reduced sensitivity of screening mammography and is related to hormone exposure. However, the effects of conjugated equine estrogens (CEEs) alone on mammographic density in diverse racial/ethnic populations are not established. We examined the effect of CEE alone on mammographic density in a subsample of the Women's Health Initiative (WHI) clinical trial participants.
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