2020•Carolina Digital Repository (University of North Carolina at Chapel Hill)Open access

Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP)

Paul M. Thompson, Scott S. Hall, Doron Gothelf, Ruth O’Hara, Heather Whiteford Erba, Joyce A. Furfaro, Joseph Piven, Helena C. Kraemer, Fumiko Hoeft, Kiralee M. Hayashi, Allan L. Reiss, Mark A. Eckert, Brenda Golianu, Swetapadma Patnaik, Jessica Ringel

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Abstract

To determine how neuroanatomic variation in children and adolescents with fragile X syndrome is linked to reduced levels of the fragile X mental retardation-1 protein and to aberrant cognition and behavior.

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Key concepts: Fragile X syndrome, Fragile x, Neuroanatomy, FMR1, Psychology, Neuroscience, Biology, Psychiatry