2022The Journal of Infectious DiseasesOpen access

A Proposal to Refer to Four Coronaviruses of Limited Human Virulence “Common Cold Coronaviruses”

Kenneth McIntosh, Stanley Perlman, Arnold S. Monto, Janet A. Englund

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Abstract

We propose the term "common cold coronaviruses," or ccCoV, to describe the four human coronaviruses commonly associated with upper respiratory tract disease - coronaviruses 229E, OC43, NL63, and HKU1. This will differentiate these previously described coronaviruses from those causing more severe disease in humans - including the viruses severe acute respiraotry syndrome coronavirus (SARS-CoV), the Middle East respiratory syndrome coronavirus (MERS-CoV) and SARS-CoV-2.

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What this paper is about

We propose the term "common cold coronaviruses," or ccCoV, to describe the four human coronaviruses commonly associated with upper respiratory tract disease - coronaviruses 229E, OC43, NL63, and HKU1. This will differentiate these previously described coronaviruses from those causing more severe disease in humans - including the viruses severe acute respiraotry syndrome coronavirus (SARS-CoV), the Middle East respiratory syndrome coronavirus (MERS-CoV) and SARS-CoV-2.

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Available abstract

We propose the term "common cold coronaviruses," or ccCoV, to describe the four human coronaviruses commonly associated with upper respiratory tract disease - coronaviruses 229E, OC43, NL63, and HKU1. This will differentiate these previously described coronaviruses from those causing more severe disease in humans - including the viruses severe acute respiraotry syndrome coronavirus (SARS-CoV), the Middle East respiratory syndrome coronavirus (MERS-CoV) and SARS-CoV-2.

Key concepts: Common cold, Coronavirus, Betacoronavirus, Middle East respiratory syndrome coronavirus, Virology, Coronavirus disease 2019 (COVID-19), Coronavirus Infections, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

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